Tossup

They’re not dehydratases, but a family of enzymes that acts on this functional group frequently contains a 7-stranded antiparallel beta sheet wrapped around a 5-turn alpha helix, forming a HotDog domain. This functional group is hydrolyzed by the ACOT family of enzymes. During fatty acid and polyketide synthesis, the growing chain is linked to ACP via this functional group. (10[2]-5[3])A SEA group undergoes an (-5[1])acyl (“ASS-il”) shift to form a peptide-linked example of this functional group in situ in a variant of native chemical ligation. Citrate synthase hydrolyzes (-5[1])this group after binding to oxaloacetate in the first step of the Krebs cycle. (-5[1])Coenzyme A is often linked to (-5[1])fatty acids (10[1])via (-5[1])this functional group. (-5[3])For 10 points, name this functional group consisting of a sulfur atom (-5[1])linking an acyl (“ASS-il”) group and an (-5[1])R group. (10[2])■END■ (10[6]0[10])

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