Tossup

Per a 2019 Nature paper, DNA in an early form of this substance found in Sylt·holm, Denmark allowed Jensen et al. to sequence a complete 5,700-year-old human genome. Terence Cosgrove developed a biodegradable version of this substance named Rev7 that was withdrawn from sale in the US after two years. A magnate who sold this substance commissioned Tournament House, the headquarters of Pasadena’s Rose Parade. This substance names an alley on Higuera (“ee-GAIR-uh”) Street flanked by 15-foot walls in San Luis Obispo, California. (10[1])A developer of this substance’s modern form, (10[1])Thomas Adams Jr., was inspired by former Mexican leader Antonio López de Santa Anna’s use (10[1])of chicle (10[12])(“CHEE-clay”). In part due (10[1])to (10[2])disruptions of MRT trains, Lee Kuan Yew pushed for a 1992 (10[1])ban on this (-5[1])substance (10[1])in Singapore. (10[1])For 10 points, what substance’s Big Red brand is sold by the Wrigley Company? ■END■ (10[1])

ANSWER: chewing gum [or bubble gum; accept Chewing Gum Alley; accept Bubblegum Alley; prompt on chicle until read; prompt on birch or birch pitch by asking “that was used in a manner analogous to what modern substance?”] (Tournament House was commissioned by William Wrigley, Jr.)
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