Tossup

Transfecting L cells with different levels of these proteins led to the discovery that these proteins can mediate cell sorting. Binding of internalins to either Met or one of these proteins begins the “zipper mechanism” that Listeria mono·cytogenes (-5[1])uses to invade cells. One of these proteins is repressed by the Snail transcription factor to promote the epithelial–mesenchymal transition. (10[1])The T-type of these (10[1])proteins is uniquely (-5[1])connected to the plasma membrane via a GPI anchor, while Masatoshi Takeichi discovered their E-type. (10[3])Beta-catenin (10[1]-5[1])binds to the cytoplasmic (10[1])tail of these proteins to link them to the actin cytoskeleton. Unlike integrins, proteins in this superfamily are responsible for mediating the attachment of cell–cell junctions. (10[2])For 10 points, (10[1])name these cell (10[1])adhesion molecules (10[1])that are named (-5[1])for their dependence on calcium. ■END■ (10[5]0[6])

Back to tossups

Buzzes

Summary